QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) was originally proposed by the US Department of Agriculture as a sample preparation method in 2003. It has been applied to a variety of sample preparations, especially for pesticide residue pretreatment. It's simpler, more economical, and faster than traditional methods.   Download brochure here. The Procedure of QuEChERS-method     Selection guide of d-SPE Products for AOAC 2007.01-Method Part Number Description Pack Size 380-00151 Extraction Salts with 50mL Centrifuge Tube, 6g MgSO4, 1.5g NaOAc 50pcs 380-00152 Extraction Salts Packets only, 6g MgSO4, 1.5g NaOAc 50pcs 380-00990-05 15 mL, 400 mg PSA, 1200 mg MgSO4 50pcs 380-00990-07 15 mL, 400 mg PSA, 400 mg C18, 1200 mg MgSO4 50pcs 380-00990-08 15 mL, 400 mg PSA, 400 mg C18, 400 mg GCB, 1200 mg MgSO4 50pcs 380-00990-17 2 mL, 50 mg PSA, 150 mg MgSO4 100pcs 380-00990-18 2 mL, 50 mg PSA, 50 mg C18, 150 mg MgSO4 100pcs 380-00990-19 2 mL, 50 mg PSA, 50 mg GCB, 150 mg MgSO4 100pcs 380-00990-20 2 mL, 50 mg PSA, 50 mg C18, 50 mg GCB, 150 mg MgSO4 100pcs   Products for EN 15662-Method Part Number Description Pack Size 380-00148 Extraction Salts with 50mL Centrifuge Tube, 4g MgSO4, 1g NaCl, 0.5g DHS, 1g TSCD 50pcs 380-00149 Extraction Salts Packets only, 4g MgSO4, 1g NaCl, 0.5g DHS, 1g TSCD 50pcs 380-00990-01 15 mL, 150 mg PSA, 15 mg GCB, 900 mg MgSO4 50pcs 380-00990-02 15 mL, 150 mg PSA, 900 mg MgSO4 50pcs 380-00990-03 15 mL, 150 mg PSA, 15 mg GCB, 885 mg MgSO4 50pcs 380-00990-04 15 mL, 150 mg PSA, 45 mg GCB, 900 MgSO4 50pcs 380-00990-06 15 mL, 150 mg PSA, 150 mg C18, 900 mg MgSO4 50pcs 380-00990-21 2 mL, 25 mg PSA, 150 mg MgSO4 100pcs 380-00990-22 2 mL, 25 mg PSA, 25 mg C18, 150 mg MgSO4 100pcs 380-00990-23 2 mL, 25 mg PSA, 2.5 mg GCB, 150 mg MgSO4 100pcs 380-00990-24 2 mL, 25 mg PSA, 7.5 mg GCB, 150 mg MgSO4 100pcs MgSO4: Magnesium sulfate, NaOAc: Sodium acetate, NaCl: Sodium chloride, TSCD: Trisodium citrate dihydrate, DHS: Disodium hydrogen citrate sesquihydrate

For connecting 0.1 ~ 0.25 mm I.D. column and 0.32 mm I.D. column. SMI (Smart Micro Inert) Union is option for connecting capillary columns that features low leakage, inertness, low dead volume and low heat capacity. This kit includes 5 ferrules, 2 pairs of unions, 1 connecting nut, and 1 pair of connecting tools Replacement ferrule 227-35025-02 Replacement union body 227-35026-01 Connecting tool, nut and union are reusable.

This is a special liner for aqueous solutions, system suitability requirements were satisfied, and good repeatability was obtained. When using a special liner for aqueous solutions repeatedly, it is recommended that it is replaced after 50 to 100 injections. Typical applications to analyze aqueous solutions: G333: Alcohol Determination of Sanitizer Gel in accordance with USP G315: Analysis of Ethanol in alcoholic beverages Using Nexis GC-2030 Liner volume is approx. 863uL

QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) was originally proposed by the US Department of Agriculture as a sample preparation method in 2003. It has been applied to a variety of sample preparations, especially for pesticide residue pretreatment. It's simpler, more economical, and faster than traditional methods.   Download brochure here. The Procedure of QuEChERS-method     Selection guide of d-SPE Products for AOAC 2007.01-Method Part Number Description Pack Size 380-00151 Extraction Salts with 50mL Centrifuge Tube, 6g MgSO4, 1.5g NaOAc 50pcs 380-00152 Extraction Salts Packets only, 6g MgSO4, 1.5g NaOAc 50pcs 380-00990-05 15 mL, 400 mg PSA, 1200 mg MgSO4 50pcs 380-00990-07 15 mL, 400 mg PSA, 400 mg C18, 1200 mg MgSO4 50pcs 380-00990-08 15 mL, 400 mg PSA, 400 mg C18, 400 mg GCB, 1200 mg MgSO4 50pcs 380-00990-17 2 mL, 50 mg PSA, 150 mg MgSO4 100pcs 380-00990-18 2 mL, 50 mg PSA, 50 mg C18, 150 mg MgSO4 100pcs 380-00990-19 2 mL, 50 mg PSA, 50 mg GCB, 150 mg MgSO4 100pcs 380-00990-20 2 mL, 50 mg PSA, 50 mg C18, 50 mg GCB, 150 mg MgSO4 100pcs   Products for EN 15662-Method Part Number Description Pack Size 380-00148 Extraction Salts with 50mL Centrifuge Tube, 4g MgSO4, 1g NaCl, 0.5g DHS, 1g TSCD 50pcs 380-00149 Extraction Salts Packets only, 4g MgSO4, 1g NaCl, 0.5g DHS, 1g TSCD 50pcs 380-00990-01 15 mL, 150 mg PSA, 15 mg GCB, 900 mg MgSO4 50pcs 380-00990-02 15 mL, 150 mg PSA, 900 mg MgSO4 50pcs 380-00990-03 15 mL, 150 mg PSA, 15 mg GCB, 885 mg MgSO4 50pcs 380-00990-04 15 mL, 150 mg PSA, 45 mg GCB, 900 MgSO4 50pcs 380-00990-06 15 mL, 150 mg PSA, 150 mg C18, 900 mg MgSO4 50pcs 380-00990-21 2 mL, 25 mg PSA, 150 mg MgSO4 100pcs 380-00990-22 2 mL, 25 mg PSA, 25 mg C18, 150 mg MgSO4 100pcs 380-00990-23 2 mL, 25 mg PSA, 2.5 mg GCB, 150 mg MgSO4 100pcs 380-00990-24 2 mL, 25 mg PSA, 7.5 mg GCB, 150 mg MgSO4 100pcs MgSO4: Magnesium sulfate, NaOAc: Sodium acetate, NaCl: Sodium chloride, TSCD: Trisodium citrate dihydrate, DHS: Disodium hydrogen citrate sesquihydrate

Fixed needle syringe with super flexible titanium alloy plunger. They are resistant to bending and sliding friction for extended lifetime, even with water soluble samples. Plunger and barrel are machined for an exact fit, so they are not interchangeable with another syringe if either part is damaged. Syringe Volume Min. Sample  Volume Needle Length (mm) Needle Gauge Needle OD (mm) Needle ID (mm) Needle tip P/N 5 μL 0.1 μL 43 23 0.64 0.15 Cone 227-35401-01 10 μL 0.2 μL 43 23 0.64 0.15 Cone 227-35400-01

Shim-pack MAqC-ODS I reversed-phase columns are packed with a silica gel containing metal and bonded octadecylsilyl group. In addition to the hydrophobic characteristics of the ODS, the metal content also provides cation-exchange effects. This increases the retention of basic compounds. Therefore, this allows use with only a buffer solution as the mobile phase for analyses that previously required using an ion pair reagent and enables using gradient elution. These characteristics are especially beneficial for analyzing water soluble vitamins and pharmaceuticals that contain a large amount of basic compounds. * To use this column efficiently: 1) To increase the retention of basic compounds, please use a buffer solution within the pH 2 to 4 range. 2) In the case of a basic substance tailing, it may be possible to improve the peak shape by increasing the salt concentration of a buffer solution. 3) The elution of basic compounds is faster by increasing the salt concentration, and it is possible to adjust retention by salt concentration.

Includes two cartridges and one holder *1 Note that a delay volume equivalent to the internal volume of the product occurs if the product is installed downstream of the gradient mixer or the confluence of two pumps. * The product service life differs according to analysis conditions, such as the mobile phase used. * Do not use the product when using a mass spectrometer as the detector, as the product may cause bleed noise. * In analysis using an ion-pairing reagent, the ion-pairing reagent may be retained in the product, influencing the retention time and peak shape. * Before connecting the analytical column, be sure to thoroughly clean the flow path with mobile phase (close to the final concentration for gradient analysis). * Note that some impurities may not be removed. * When performing high-pressure analysis exceeding 35 MPa with a UHPLC system, connect the gradient mixer to the Ghost Trap DS-HP with pipe for UHPLC (e.g. 228-53137-97).

General purpose column for reversed-phase chromatography Highest hydrophobic retention among Shim-pack Velox series Compatible with moderately acidic to neutral mobile phases (pH 2-8) Shim-pack Velox C18 is a traditional end-capped C18-bonded phase which offers the highest hydrophobic retention of any Shim-pack Velox phases and is applicable to a wide range of applications such as pharmaceutical, food, environmental and clinical and neutrals at moderately low and mid-range pH.  

Designed and intended specifically for use under low pH condition, Shim-pack Velox SP (Sterically Protected)-C18 offers a well balanced retention profile with a long life time even under harsh, acidic condition needed for LC/MS(/MS) analysis. Sterically protected to resist strongly acidic (pH 1-3) mobile phase condition Well balanced retention profile Suitable for LC/MS(/MS) analysis

Shim-pack Scepter C4-300 is wide-pore organic silica hybrid reversed phase columns recommended for the separation of proteins such as monoclonal antibodies and mid-sized molecules such as oligonucleic acids and peptides that may not be retained on 100-120Å pore size columns due to size-exclusion effects. The organic silica hybrid base material is highly stable even at high temperatures under acidic and basic mobile phase conditions. Pore sizes are optimized for large molecular weight compounds and dispersed uniformly in the column, resulting in symmetrical peak shapes and increased resolution of antibodies and nucleic acids compared to a smaller pore size column. Shim-pack Scepter C4-300 is also effective for high-sensitivity LC/MS analysis, producing good peak shapes even under weak ionpairing conditions using a formic acid mobile phase Peptide Analysis Example Shim-pack Scepter C18-300 and C4-300 made with 300 Å (30 nm) pore size packing material. The larger pore size is recommended for the analysis of mid-sized and large-sized molecules with molecular weights above 5000 to enable retention and avoid size-exclusion effects. This analysis of a mixed sample of four different peptides and proteins demonstrated good peak shapes and favorable separation of insulin and ribonuclease A due to the pore size that was large enough to allow proper diffusion of these large molecular weight compounds.  

Shim-pack GIST C18-AQ achieves strong retention of hydrophilic highly polar compounds compared to general C18 columns, while maintaining high inertness and durability in highly or 100 % aqueous mobile phases. Shim-pack GIST C18-AQ is also able to reduce the absorption of basic and acidic compounds and achieve superior peak shapes in the analysis of metal complexes.  

Shim-pack GIS RP-Shield contains a polar functional group embedded between silica surface and an octadecyl group, making it stable in 100 % aqueous mobile phases without phase collapse. The embedded polar functional group is also extremely base deactivated, which enables the column to provide superior peak shape for acids. Shim-pack GIS RP-Shield provides unique selectivity as hydrogen bonding interactions, making it suitable for separations that cannot be achieved by other modes, such as hydrophobic interactions or π-π interactions.

Shim-pack GIST C18 has superior inertness, which improves analysis precision and increases column stability. In addition, it can be used to analyze strong ionic compounds and difficult to absorb samples, which helps to obtain symmetrical peaks and high reproducibility. Furthermore, because of the new silica gel, Shim-pack GIST C18 is suitable for wider pH (1-10) analysis at a consistent performance. This enables use of a silica-based column under alkaline conditions.

Shim-pack Bio HIC Column is a hydrophobic interaction chromatography (HIC) column packed with butyl bonded hydrophilic nonporous polymer particles (4 μm). HIC is suitable for the separation of anlaytes with slightly different hydrophobicity, such as antibody-drug conjugate (ADC) with different drug-antibody ratios (DAR). Shim-pack Bio HIC can be used for the analysis of DAR of ADC with relatively low pressure and high resolution. Need for DAR Analysis in ADCs ADCs consist of lysine and cysteine residues of a monoclonal antibody (mAb) and small-molecule drugs (Fig.1). However, since mAbs contain multiple amino acid residues involved in their binding, the mAbs are known to form heterogeneous ADCs with different binding numbers and binding sites. These heterogeneities can affect a drug's efficacy and safety, making analysis of the drug-antibody ratio (DAR) essential to determine the quality characteristics of ADCs. In addition, maintaining the distribution of DAR within a certain range enables quality assurance in ADC manufacturing.   Excellent Reproducibility to Help Calculate DAR Reproducibility of area values obtained from repeat injections (n= 6) of cysteine-conjugated ADC samples and an example of an automated DAR calculation report are shown below. (DAR can be calculated automatically using LabSolutions DB/CS custom reporting.) The Shim-pack BIO HIC, developed for biopharmaceutical analysis, makes it possible to detect slight differences in hydrophobicity of small-molecule drugs and perform rapid DAR analysis with high resolution. Download flyer

Shim-pack Bio IEX Columns are available in Q (quaternary ammonium) and SP (sulfopropyl) chemistries and are based on porous (Q and SP columns) and non-porous (Q-NP and SP-NP columns) hydrophilic polymers with low nonspecific adsorption. The porous particles offer excellent binding capacity with exceptionally high efficiency and the non-porous particles offer high efficiency and exceptional resolution.

Excellent Seperation Performance of Peptides Typically, in order to obtain good peak shape of peptides under reversed phase chromatography, TFA containing mobile phases are frequently used which the ion pairing effect is relatively strong. However, TFA could cause ion suppression in LC/MS(/MS) analysis. Excellent peak shape and separation performance for peptides could be achieved on the Shim-pack Arata LC column even under formic acid (weak ion paring acid) containing mobile phase conditions, which are suitable for LC/MS(/MS) without the use of typical ion pairing agents. Increased Assurance of Peptide Analysis ~ Shim-pack Arata Peptide C 18 column ~ In order to ensure lot-to-lot reproducibility in peptide analysis, each lot of Shim-pack Arata Peptide C18material is tested using a mixture of peptide standards in addition to the standard Shim-pack Arata C18 lot QCtest. This test is carried out under severe condition using 0.1 % formic acid mobile phase to help ensure consistent column performance for requirements of customers under regulated requirements.use of typical ion pairing agents. Excellent Seperation Performance of Peptides When analyzing peptides on a typical ODS column with 0.1% formic acid mobile phase, not only poor peak shape but also long equilibration time required to obtain stable retention times and area is a common problem. Shim-pack Arata Peptide C18 columns can be rapidly equilibrated even in 0.1% formic acid containing mobile phase, achieving excellent peak shape, stable retention andarea of peptides at the same time. Both columns were new columns (shipping solvent: acetonitrile) and equilibrated with mobile phase without any conditioning. Angiotensin I was analyzed after a certain period of equilibration and retention time, symmetry factor and area of Angiotensin I were compared. The typical ODS showed poor peak symmetry and unstable retention time even after 360 minutes of equilibration. In contrast, Shim-pack Arata peptide C18 already showed stable retention after 30 minutes of equilibration and excellent peak shape was obtained.

Excellent Seperation Performance of Peptides Typically, in order to obtain good peak shape of peptides under reversed phase chromatography, TFA containing mobile phases are frequently used which the ion pairing effect is relatively strong. However, TFA could cause ion suppression in LC/MS(/MS) analysis. Excellent peak shape and separation performance for peptides could be achieved on the Shim-pack Arata LC column even under formic acid (weak ion paring acid) containing mobile phase conditions, which are suitable for LC/MS(/MS) without the use of typical ion pairing agents. Increased Assurance of Peptide Analysis ~ Shim-pack Arata Peptide C 18 column ~ In order to ensure lot-to-lot reproducibility in peptide analysis, each lot of Shim-pack Arata Peptide C18material is tested using a mixture of peptide standards in addition to the standard Shim-pack Arata C18 lot QCtest. This test is carried out under severe condition using 0.1 % formic acid mobile phase to help ensure consistent column performance for requirements of customers under regulated requirements.use of typical ion pairing agents. Excellent Seperation Performance of Peptides When analyzing peptides on a typical ODS column with 0.1% formic acid mobile phase, not only poor peak shape but also long equilibration time required to obtain stable retention times and area is a common problem. Shim-pack Arata Peptide C18 columns can be rapidly equilibrated even in 0.1% formic acid containing mobile phase, achieving excellent peak shape, stable retention andarea of peptides at the same time. Both columns were new columns (shipping solvent: acetonitrile) and equilibrated with mobile phase without any conditioning. Angiotensin I was analyzed after a certain period of equilibration and retention time, symmetry factor and area of Angiotensin I were compared. The typical ODS showed poor peak symmetry and unstable retention time even after 360 minutes of equilibration. In contrast, Shim-pack Arata peptide C18 already showed stable retention after 30 minutes of equilibration and excellent peak shape was obtained.

Excellent Seperation Performance of Peptides Typically, in order to obtain good peak shape of peptides under reversed phase chromatography, TFA containing mobile phases are frequently used which the ion pairing effect is relatively strong. However, TFA could cause ion suppression in LC/MS(/MS) analysis. Excellent peak shape and separation performance for peptides could be achieved on the Shim-pack Arata LC column even under formic acid (weak ion paring acid) containing mobile phase conditions, which are suitable for LC/MS(/MS) without the use of typical ion pairing agents. Increased Assurance of Peptide Analysis ~ Shim-pack Arata Peptide C 18 column ~ In order to ensure lot-to-lot reproducibility in peptide analysis, each lot of Shim-pack Arata Peptide C18material is tested using a mixture of peptide standards in addition to the standard Shim-pack Arata C18 lot QCtest. This test is carried out under severe condition using 0.1 % formic acid mobile phase to help ensure consistent column performance for requirements of customers under regulated requirements.use of typical ion pairing agents. Excellent Seperation Performance of Peptides When analyzing peptides on a typical ODS column with 0.1% formic acid mobile phase, not only poor peak shape but also long equilibration time required to obtain stable retention times and area is a common problem. Shim-pack Arata Peptide C18 columns can be rapidly equilibrated even in 0.1% formic acid containing mobile phase, achieving excellent peak shape, stable retention andarea of peptides at the same time. Both columns were new columns (shipping solvent: acetonitrile) and equilibrated with mobile phase without any conditioning. Angiotensin I was analyzed after a certain period of equilibration and retention time, symmetry factor and area of Angiotensin I were compared. The typical ODS showed poor peak symmetry and unstable retention time even after 360 minutes of equilibration. In contrast, Shim-pack Arata peptide C18 already showed stable retention after 30 minutes of equilibration and excellent peak shape was obtained.

Unprecedented Resolution and Peak Shape of Basic Compounds Even for LC columns that claim to be designed for basic compounds, adequate resolution often can not be obtained due to problems such as leading of highly polar basic compounds, peak shape deterioration of acidic compounds, or long equilibration time required for low ionic strength acidic mobile phase. All of these issues have been solved with Shim-pack Arata that was specifically designed to give unmatched peak shape for basic compounds. Unmatched Peak Shape Elegantly Designed for A Wide Range of Compounds Unmatched peak shape of basic compounds could be achieved while maintaining good peak shape for acidic compounds with Shim-pack Arata LC columns. Even with low ionic strength acidic mobile phase, such as 0.1% formic acid containing mobile phase, excellent peak shape of both amitriptyline (a basic compound) and benzoic acid (an acidic compound) could be achieved. Excellent Separation Performance for Peptides Even with Weak Ion Paring Acids In order to obtain good peak shape of peptides under reversed phase chromatography, TFA containing mobile phases are frequently used which the ion pairing effect is relatively strong. However, TFA could cause ion suppression in LC/MS (/MS) analysis. Excellent peak shape and separation performance for peptides could be achieved on the Shim-pack Arata LC column even with 0.1 % formic acid (weak ion paring acid) containing mobile phase.  

Includes two Press-Tight® connectors and a 2.5 m column. Protects detector and valves; connects between column and detector or valve. Eliminates detector spikes and scratches in valve rotors.

Low-polarity phase: Crossbond™ silarylene phase 1,4-bis(dimethylsiloxy) phenylene dimethyl polysiloxane Engineered to be a low-bleed GCMS column. Excellent inertness for active compounds. General-purpose columns—ideal for GCMS analysis of semi-volatiles, polycyclic aromatic compounds, chlorinated hydrocarbons, phthalates, phenols, amines, organochlorine pesticides, organophosphorus pesticides, drugs, solvent impurities, and hydrocarbons. Similar phases: DB-5ms UI, DB-5ms, VF-5ms, SLB-5ms For SH-I-5Sil MS with Integrated Guard column in this dimension, plase refer to 221-76162-30 and 221-76161-30

Extend column lifetime. Excellent inertness—obtain lower detection limits for active compounds. Sharper chromatographic peaks by utilizing retention gap technology. Maximum temperature: 360 °C.

Reliability Certified Quality (CQ) vial include a product certification. The vials are shipped with a certificate that certifies that the quantity of organic impurities leached into the vial is less than 10 μg C/L. CQ vial are pre-cleaned. This process prevents accidental contamination during cleaning, drying, or storage in the laboratory. CQ vial are sealed with a cap and septum and packed in a plastic box that inhibits dust or other matter. Download brochure here. Efficiency CQ vial are pre-cleaned. They can be used immediately after opening the box. Cleaning and drying operations are no longer needed. It also eliminates the need to carefully avoid contamination during storage. That means significantly less time and space are required for operations.   Measurement Method A large thoroughly-cleaned glass bottle was filled with ultrapure water. That water was dispensed from the bottle into a vial and the TOC level was measured in both the bottle and vial. Using the bottle water measurement results as blank data, the quantity leached from the vial was determined by subtracting the blank measurement results from the vial measurement results. Leaching was evaluated in that way a total of six times, including three times for vials (reused vials) cleaned using a laboratory equipment cleaning machine and three times using CQ pre-cleaned vials. CQ vial were significantly more effective at inhibiting leaching than the vials cleaned in the cleaning machine. Therefore, the use of CQ vial should be considered not only by customers measuring pure water, but also by customers that want to avoid contamination during vial cleaning, drying, and storage, and customers looking to save the time and space required for cleaning, drying, and storing vials. 

20mL Headspace crimp clear vial

Features Low adsorption vessels treated specially Minimized adsorption of bases, acids and neutrals Superior quality control TORAST -H Glass Technology eliminates the risk of adsorption to the glass surface of the vials Glass, the material of vials, contains metal oxides. Oxides of metals have a high ionizing tendency to be Si-O-M (metal silanolate), which may cause ionic adsorption with basic compounds in the sample. TORAST-H Glass Technology uses special processing to remove metals from the glass and suppress adsorption of basic compounds. Minimized adsorption of bases, acids & neutrals In general, giving a positive charge to the glass surface suppresses the adsorption of the basic compounds, but conversely, it causes the adsorption of the acidic compounds. TORAST-H Glass Vials minimize adsorption of both types of compounds. Low adsorption for long-term storage When a sample is stored in a general vial for a long time, the sample may adsorb into the surface of the vial, causing the reproducibility to be poor. The TORAST-H Glass Vial contains low adsorption characteristics that makes it excellent for long term sample storage.

Black PP cap, Silicone white/PTFE red for LabTotal vial LCMS, 100/pk

Reduces the Adsorption of Basic Compounds on the Surface of the Glass Vial. This improves quantitative accuracy in the analysis of trace basic compounds.   Quality certificate proving suitability to LCMS / GCMS This product can be used as a vial for high-sensitivity analysis in GCMS and LCMS   Wide Mouth with Preset Cap and Septum Improves Ease of Use  This shortens the time needed for sample preparation and reduces human error.   Mass Spec Quality Certificate Provided This confirms that there was an absence of elution components from the vial in random inspections using LC/MS and GC/MS. Therefore, this product can be used with confidence, with no concern for ghost peaks originating from the vial. For replacement cap/septa, please use 226-84340-01