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SHIMSEN Solid-Phase Extraction

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Solid Phase Extraction (SPE) Columns and Cartridges

Solid Phase Extraction (SPE) is a powerful technique used in analytical chemistry to purify, concentrate, and isolate specific compounds or analytes from a sample. It serves as a crucial step in applications like toxicology tests, environmental monitoring, and pharmaceutical research, among others. The technique uses solid media contained in columns or cartridges to selectively bind the target analytes and separate them from other substances, ensuring a cleaner sample for subsequent analysis.

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The success of an SPE procedure rests on the quality of the columns and cartridges used. Reliable SPE columns and cartridges are essential for obtaining precise, accurate, and repeatable results. Poor-quality consumables can lead to issues such as low recovery rates, inconsistent flows, and even contamination, which would compromise the integrity of the analysis.

This is where ShopShimadzu comes in. We offer an exceptional range of SPE consumables that meet and exceed industry standards for quality and reliability. Our columns and cartridges are engineered using state-of-the-art materials and undergo rigorous quality control tests. They come in various sizes, phases, and formats to suit a broad range of applications. Whether you are working on bioanalytical assays, environmental testing, or food safety analysis, you can trust our SPE consumables to deliver the performance and reliability you need. By choosing our high-quality SPE columns and cartridges, you invest in consumables that enable you to conduct more effective, reliable, and accurate analyses.

Our Range of SPE Consumables

When it comes to SPE columns and cartridges, ShopShimadzu provides an extensive selection designed to meet diverse analytical requirements. We offer various sizes and formats along with different separation modes and volumes to suit your specific application needs.

Separation Modes

  • Mixed Mode Reversed Phase Cation Exchange: Ideal for the extraction of cationic compounds from complex matrices, this mode combines the selectivity of reversed-phase and cation-exchange mechanisms. It's widely used in pharmaceuticals to isolate basic drugs from plasma or urine.
  • Proprietary: The proprietary mode of SPE columns offers unique selectivity and retention properties, often tailored for specialised applications. Information on this mode is typically proprietary to maintain a competitive edge.
  • Mixed Mode Reversed Phase Anion Exchange: Best suited for separating anionic compounds, this mode is often used in environmental analysis for isolating acidic pesticides from soil or water samples.
  • Reversed Phase: This is the most commonly used mode for a wide range of applications of SPE columns including peptide purification, drug screening, and more. It's particularly effective for non-polar and moderately polar compounds.
  • Normal Phase: Typically used for the separation of polar compounds, normal phase is often chosen for applications like the isolation of flavonoids from plant extracts.
  • Cation Exchange: Specialised for targeting positively charged compounds, this mode in SPE columns is used in areas like food testing for the extraction of amines and amino acids.
  • Anion Exchange: Geared towards the extraction of negatively charged analytes, it's extensively used in water quality testing for substances like anionic surfactants.
  • Carbon: Carbon mode offers high retention for non-polar to moderately polar compounds. It is especially useful in forensic applications for drug detection.
  • Special: These SPE columns are designed for unique and specialised applications that don't fit into the conventional modes, like chiral separations or the isolation of large biomolecules.


Volume/mL

Our SPE columns and cartridges come in an array of volume sizes to suit various application needs. Specifically, the available volumes include 1 mL, 3 mL, 6 mL, 12 mL, 20 mL, and 60 mL. This range of sizes gives you the flexibility to select the most suitable volume for your unique analytical requirements, thereby enhancing both efficiency and reliability in your work.

Choosing The Right SPE Column Or Cartridge

Choosing the right SPE column or cartridge is critical for ensuring optimal analytical results. Here are some key factors to consider:

  • Sample Matrix Considerations: The complexity and nature of your sample matrix dictate which column or cartridge will best suit your needs. Some SPE columns are specially designed for aqueous samples, while others may be suited for organic solvents or biological matrices.
  • Analyte Characteristics: It's crucial to understand the characteristics of the analytes you wish to isolate. Parameters like size, polarity, and charge significantly impact which type of stationary phase will be most effective. For instance, an SPE column designed for hydrophobic interactions would be unsuitable for polar compounds.
  • Column Dimension and Compatibility: The physical dimensions of the column, including volume and sorbent weight are important. length and diameter, as well as compatibility with your existing SPE system, are important. Incorrect sizing can lead to problems like poor recovery. increased back pressure and inefficient separation. The luer slip design ensures compatibility with various vacuum manifolds.


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